Health

Health & illness

Most health problems in captive leopard geckos are caused by husbandry issues — incorrect temperatures, bad substrate, or missing supplementation. Knowing what to look for and what causes it is the fastest route to fixing it.

Find a reptile-specialist vet before you need one. A standard small animal vet may have no experience with reptiles. Search the RCVS Find a Vet directory (rcvs.org.uk) or ask in reputable UK leo keeper communities for recommendations in your area.
Warning signs — see a vet
Rubbery, soft, or visibly bowed limbs
Tremors, twitching, or seizures
Tail base noticeably thinner than the neck
Refusing food for more than 2 weeks without a clear reason
Swollen limbs, jaw, or belly
Watery, bloody, or unusually foul-smelling stool
Eyes sunken or unable to fully open
Difficulty lifting the head or walking
Wheezing, clicking, or open-mouth breathing
Visible mucus around nostrils or mouth
Progressive weight loss despite eating
Straining without passing faeces for more than 2 weeks
If you notice any of these signs, consult a reptile-specialist vet promptly. Many conditions are treatable when caught early and become difficult to reverse when left untreated.
Common conditions
Metabolic Bone Disease (MBD)
Vet urgently
Cause

Calcium deficiency, D3 deficiency, or imbalanced Ca:P ratio from insufficient supplementation.

Signs
  • Rubbery or soft limbs
  • Tremors and twitching
  • Difficulty walking or lifting head
  • Jaw deformity or swelling
  • Loss of appetite
Treatment

Vet visit is essential. MBD is reversible in early stages with calcium supplementation and UVB correction. Advanced MBD with skeletal deformity cannot be fully reversed.

Prevention

Dust every feeding with calcium for juveniles, every other feeding for adults. Keep a plain calcium dish in the enclosure always.

Cryptosporidiosis (Crypto)
Vet urgently
Cause

Cryptosporidium varanii — a microscopic gut parasite. Spread via faecal-oral route. Can survive on surfaces for months.

Signs
  • Progressive weight loss despite eating
  • Regurgitation of food
  • Tail wasting — gecko appears 'pinched' behind the ribs
  • Lethargy
  • Worsening over weeks
Treatment

There is no cure. Supportive care can slow progression. Strict isolation from all other reptiles immediately. Equipment must be bleached or destroyed — crypto resists most disinfectants.

Prevention

Quarantine all new geckos for a minimum of 90 days. Never share equipment between animals without sterilisation. Source geckos from reputable breeders who health-test their stock.

Retained shed (dysecdysis)
See a vet
Cause

Low humidity, incorrect temperatures, inadequate rough surfaces, or underlying health issues preventing complete shed.

Signs
  • Dull patches of skin after shed
  • Skin visible on toes, eye caps, or tail tip
  • Toe swelling
  • Cloudy eye after shed is complete
Treatment

Warm soak for 10–15 minutes, then gentle removal with damp cotton bud. Eye caps: vet visit. Toes: treat the same day — do not wait.

Prevention

Maintain a functional humid hide. Provide rough surfaces (slate, cork bark). Check every shed within 24 hours.

Parasites (pinworms, coccidia)
See a vet
Cause

Internal parasites are common in wild-caught geckos and possible in any captive gecko. Usually manageable rather than fatal.

Signs
  • Loose or unusual stools
  • Mucus in faeces
  • Unexplained weight loss
  • Lethargy
  • Bloating
Treatment

Faecal test from a reptile vet — do not treat without a diagnosis. Antiparasitic medications are prescription-only and differ depending on the parasite.

Prevention

Annual faecal testing recommended. Quarantine new animals. Never introduce wild-caught insects to the enclosure.

Respiratory infection (RI)
See a vet
Cause

Usually caused by incorrect temperatures (too cold) or too-high humidity. Bacteria or viral secondary infection follows.

Signs
  • Mucus around nostrils or mouth
  • Wheezing or clicking sounds when breathing
  • Open-mouth breathing
  • Lethargy
  • Reduced appetite
Treatment

Vet visit. Antibiotics for bacterial RI. Correct the husbandry simultaneously — if the environment that caused it remains unchanged, the infection will return.

Prevention

Maintain correct temperatures at all times. Do not let ambient humidity exceed 50%. Ensure ventilation is adequate.

Impaction
See a vet
Cause

Ingestion of substrate (sand, gravel, walnut shell, calcium sand) that cannot pass through the digestive tract.

Signs
  • Straining to defecate
  • Bloating
  • Loss of appetite
  • Lethargy
  • No faeces for more than 2 weeks
Treatment

Warm soaks, gentle belly massage along the direction of the gut. Vet visit if no improvement within 48 hours — impaction can be fatal if left untreated.

Prevention

Use safe substrate. Juveniles especially should never be on loose substrate. Feed in a separate enclosure if your gecko consistently swallows substrate when hunting.

Tail loss (autotomy)
Monitor
Cause

Voluntary self-defence mechanism triggered by stress, handling of the tail, or attack by another animal.

Signs
  • Tail separates at a fracture plane
  • Stump bleeds briefly then seals
  • Gecko continues eating and behaving normally within hours
Treatment

Keep the enclosure clean and dry. Dab the stump with dilute betadine if available. The wound will seal naturally — do not bandage. A regenerated tail will grow within 6–8 weeks.

Prevention

Never grab or restrain a gecko by the tail. Immediately separate any cohoused geckos.

Egg binding (dystocia)
Vet urgently
Cause

Female geckos produce eggs even without a male. Egg binding occurs when eggs cannot be passed — due to size, poor condition, or lack of a laying site.

Signs
  • Visible bulges in the lower abdomen
  • Straining without producing eggs
  • Lethargy, loss of appetite
  • Swollen, firm belly that doesn't resolve
Treatment

Vet visit urgently. Oxytocin injection may be sufficient; in severe cases surgical removal is required. Do not wait — egg binding is fatal without intervention.

Prevention

Provide a laying box (moist sand or coco coir, deep enough to dig) for all female geckos, even if no male is present.